A new European Patent granted

The members of the Department of Inorganic Chemistry in collaboration with the Department of Cell Biology and Genetics have achieved further significant milestone in the research of novel highly effective potential anticancer drugs based on copper. The newly granted European patent entitled “Utilization of copper complexes involving 2-phenyl-3-hydroxy-4(1H)-quinolinone and 1,10-phenanthroline derivatives for the preparation of drugs for the treatment of tumour diseases“ (EP2650000 B1; inventors: Zdeněk Trávníček, Ján Vančo, Roman Buchtík, Zdeněk Dvořák) provides the protection for a group of copper(II) complexes having the general formula [Cu(qui)(L2)]X, where qui represents an anion of 1-azaflavon-3-ol and L2 is a derivative of 1,10-phenanthroline, and their use in the treatment of various types of human cancer (e.g. lung carcinoma, cervical carcinoma, malignant melanoma, ovarian carcinoma, including the cisplatin-resistant ovarian carcinoma, and prostate carcinoma).





Date: 15. mar 2017 | Author: agch

Department of Inorganic Chemistry

Faculty of Science
Palacký University in Olomouc

17. listopadu 12
CZ-771 46 Olomouc
Czech Republic

tel: +420 585 634 351
fax: +420 585 634 357
email : agch(at)upol.cz